node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDX31649.1 | CDX31651.1 | MPLDJ20_140359 | MPLDJ20_140360 | Hypothetical protein; No homology to any previously reported sequences. | Riboflavin synthase alpha chain. | 0.773 |
CDX31649.1 | CDX31659.1 | MPLDJ20_140359 | MPLDJ20_140363 | Hypothetical protein; No homology to any previously reported sequences. | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | 0.441 |
CDX31649.1 | nrdR | MPLDJ20_140359 | MPLDJ20_140362 | Hypothetical protein; No homology to any previously reported sequences. | Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.773 |
CDX31649.1 | ribD | MPLDJ20_140359 | MPLDJ20_140361 | Hypothetical protein; No homology to any previously reported sequences. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.773 |
CDX31651.1 | CDX31649.1 | MPLDJ20_140360 | MPLDJ20_140359 | Riboflavin synthase alpha chain. | Hypothetical protein; No homology to any previously reported sequences. | 0.773 |
CDX31651.1 | CDX31659.1 | MPLDJ20_140360 | MPLDJ20_140363 | Riboflavin synthase alpha chain. | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | 0.441 |
CDX31651.1 | glyA-2 | MPLDJ20_140360 | MPLDJ20_140364 | Riboflavin synthase alpha chain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.414 |
CDX31651.1 | nrdR | MPLDJ20_140360 | MPLDJ20_140362 | Riboflavin synthase alpha chain. | Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.814 |
CDX31651.1 | ribD | MPLDJ20_140360 | MPLDJ20_140361 | Riboflavin synthase alpha chain. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
CDX31659.1 | CDX31649.1 | MPLDJ20_140363 | MPLDJ20_140359 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | Hypothetical protein; No homology to any previously reported sequences. | 0.441 |
CDX31659.1 | CDX31651.1 | MPLDJ20_140363 | MPLDJ20_140360 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | Riboflavin synthase alpha chain. | 0.441 |
CDX31659.1 | glyA-2 | MPLDJ20_140363 | MPLDJ20_140364 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.563 |
CDX31659.1 | nrdR | MPLDJ20_140363 | MPLDJ20_140362 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.441 |
CDX31659.1 | ribD | MPLDJ20_140363 | MPLDJ20_140361 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.442 |
glyA-2 | CDX31651.1 | MPLDJ20_140364 | MPLDJ20_140360 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Riboflavin synthase alpha chain. | 0.414 |
glyA-2 | CDX31659.1 | MPLDJ20_140364 | MPLDJ20_140363 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | 0.563 |
glyA-2 | nrdR | MPLDJ20_140364 | MPLDJ20_140362 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.478 |
glyA-2 | ribD | MPLDJ20_140364 | MPLDJ20_140361 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.481 |
nrdR | CDX31649.1 | MPLDJ20_140362 | MPLDJ20_140359 | Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Hypothetical protein; No homology to any previously reported sequences. | 0.773 |
nrdR | CDX31651.1 | MPLDJ20_140362 | MPLDJ20_140360 | Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Riboflavin synthase alpha chain. | 0.814 |