STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDX34681.1Hypothetical protein; No homology to any previously reported sequences. (196 aa)    
Predicted Functional Partners:
CDX34683.1
Hypothetical protein; No homology to any previously reported sequences.
       0.773
guaA
GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
    
  0.756
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.572
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
    
  0.553
CDX28746.1
Peptidase M23.
    
 0.542
thyA
Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.541
CDX31365.1
N-acetylmuramoyl-L-alanine amidase.
    
  0.518
cmk
Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.515
tdk
Thymidine kinase/deoxyuridine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.515
CDX30992.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the CinA family.
    
  0.506
Your Current Organism:
Mesorhizobium plurifarium
NCBI taxonomy Id: 69974
Other names: CIP 105884, JCM 21566, LMG 11892, LMG:11892, M. plurifarium, Mesorhizobium sp. LMG 11892, NBRC 102498, Rhizobium sp. LMG 7836, Rhizobium sp. LMG 7854
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