node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDX36580.1 | CDX41182.1 | MPLDJ20_20615 | MPLDJ20_320050 | DnaK-type molecular chaperone DnaK. | Histidine kinase (fragment). | 0.998 |
CDX36580.1 | groEL | MPLDJ20_20615 | MPLDJ20_110451 | DnaK-type molecular chaperone DnaK. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.927 |
CDX36580.1 | groL | MPLDJ20_20615 | MPLDJ20_130033 | DnaK-type molecular chaperone DnaK. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.927 |
CDX36580.1 | groL-2 | MPLDJ20_20615 | MPLDJ20_320087 | DnaK-type molecular chaperone DnaK. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.927 |
CDX36580.1 | groS-2 | MPLDJ20_20615 | MPLDJ20_320088 | DnaK-type molecular chaperone DnaK. | 10kDa chaperonin (Protein Cpn10) (groES protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.878 |
CDX36580.1 | grpE | MPLDJ20_20615 | MPLDJ20_60724 | DnaK-type molecular chaperone DnaK. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.997 |
CDX36580.1 | hslU | MPLDJ20_20615 | MPLDJ20_230056 | DnaK-type molecular chaperone DnaK. | ATPase component of the HslUV protease, also functions as molecular chaperone; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.751 |
CDX36580.1 | htpG | MPLDJ20_20615 | MPLDJ20_320083 | DnaK-type molecular chaperone DnaK. | Molecular chaperone HSP90 family; Molecular chaperone. Has ATPase activity. | 0.997 |
CDX41182.1 | CDX36580.1 | MPLDJ20_320050 | MPLDJ20_20615 | Histidine kinase (fragment). | DnaK-type molecular chaperone DnaK. | 0.998 |
CDX41182.1 | dnaK | MPLDJ20_320050 | MPLDJ20_200107 | Histidine kinase (fragment). | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.998 |
CDX41182.1 | groEL | MPLDJ20_320050 | MPLDJ20_110451 | Histidine kinase (fragment). | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.890 |
CDX41182.1 | groL | MPLDJ20_320050 | MPLDJ20_130033 | Histidine kinase (fragment). | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.890 |
CDX41182.1 | groL-2 | MPLDJ20_320050 | MPLDJ20_320087 | Histidine kinase (fragment). | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.890 |
CDX41182.1 | groS-2 | MPLDJ20_320050 | MPLDJ20_320088 | Histidine kinase (fragment). | 10kDa chaperonin (Protein Cpn10) (groES protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.814 |
CDX41182.1 | grpE | MPLDJ20_320050 | MPLDJ20_60724 | Histidine kinase (fragment). | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.860 |
CDX41182.1 | hslU | MPLDJ20_320050 | MPLDJ20_230056 | Histidine kinase (fragment). | ATPase component of the HslUV protease, also functions as molecular chaperone; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.815 |
dnaK | CDX41182.1 | MPLDJ20_200107 | MPLDJ20_320050 | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Histidine kinase (fragment). | 0.998 |
dnaK | groEL | MPLDJ20_200107 | MPLDJ20_110451 | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.961 |
dnaK | groL | MPLDJ20_200107 | MPLDJ20_130033 | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.960 |
dnaK | groL-2 | MPLDJ20_200107 | MPLDJ20_320087 | Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.960 |