STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dfpFused 4'-phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (491 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.977
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
 
 0.957
coaA
Pantothenate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.951
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.950
aatA-2
Aspartate aminotransferase A (AspAT); Function of strongly homologous gene; enzyme.
  
  0.909
CDX44094.1
Class I and II aminotransferase.
  
  0.909
mazG
Nucleoside triphosphate pyrophosphohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
  0.891
cysB
Cysteine synthase.
    
  0.885
cysK
Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.885
cysK-2
Cysteine synthase.
    
  0.885
Your Current Organism:
Mesorhizobium plurifarium
NCBI taxonomy Id: 69974
Other names: CIP 105884, JCM 21566, LMG 11892, LMG:11892, M. plurifarium, Mesorhizobium sp. LMG 11892, NBRC 102498, Rhizobium sp. LMG 7836, Rhizobium sp. LMG 7854
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