STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDX46854.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (139 aa)    
Predicted Functional Partners:
CDX46853.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.942
CDX12793.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.805
ruvA
Component of RuvABC resolvasome, regulatory subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.776
CDX46351.1
Transcriptional regulator, CopG family.
 
 
   0.772
CDX14425.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
   0.705
CDX36733.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
   0.705
CDX39666.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
   0.705
ruvB
Holliday junction DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.646
ruvC
Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.634
hsdR
Endonuclease R; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
     0.519
Your Current Organism:
Mesorhizobium plurifarium
NCBI taxonomy Id: 69974
Other names: CIP 105884, JCM 21566, LMG 11892, LMG:11892, M. plurifarium, Mesorhizobium sp. LMG 11892, NBRC 102498, Rhizobium sp. LMG 7836, Rhizobium sp. LMG 7854
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