STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB06331.1COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: ele:Elen_0577 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Putative uncharacterized protein; IMG reference gene:2503574983; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (363 aa)    
Predicted Functional Partners:
AEB07001.1
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.977
AEB06248.1
NUDIX hydrolase; COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR000086; KEGG: ttu:TERTU_3249 isopentenyl-diphosphate delta-isomerase; PFAM: NUDIX hydrolase; SPTR: Putative uncharacterized protein; IMG reference gene:2503574895; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1.
  
 
 0.957
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.940
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.836
AEB06332.1
COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509:IPR005886; KEGG: apv:Apar_0346 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative uncharacterized protein; TIGRFAM: UDP-glucose 4-epimerase; IMG reference gene:2503574984; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
  
 0.809
AEB06330.1
InterPro IPR002477; KEGG: apv:Apar_0344 peptidoglycan-binding domain 1 protein; PFAM: Peptidoglycan-binding domain 1 protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503574982; PFAM: Putative peptidoglycan binding domain.
 
   
 0.704
AEB06965.1
InterPro IPR013026:IPR019734:IPR001440; KEGG: apv:Apar_0669 tetratricopeptide domain protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575646; PFAM: Tetratricopeptide repeat.
 
 
 0.673
AEB07755.1
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001182:IPR005311:IPR001460; KEGG: apv:Apar_1344 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; cell cycle protein; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503576476; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; Cell cycle protein; Belongs to the SEDS family.
 
  
 0.657
AEB06836.1
COGs: COG3883 conserved hypothetical protein; KEGG: ccu:Ccur_04880 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575511.
 
     0.654
AEB07259.1
COGs: COG0143 Methionyl-tRNA synthetase; InterPro IPR015413; KEGG: apv:Apar_0881 methionine--tRNA ligase; PFAM: tRNA synthetase class I (M); PRIAM: Methionine--tRNA ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575958; PFAM: tRNA synthetases class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.637
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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