STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB06358.1Transcriptional regulator, XRE family; COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR001387:IPR019759; KEGG: ccu:Ccur_03030 SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: helix-turn-helix domain protein; Peptidase S24/S26A/S26B, conserved region; SMART: helix-turn-helix domain protein; SPTR: Putative prophage L54a, repressor protein; IMG reference gene:2503575010; PFAM: Helix-turn-helix; Peptidase S24-like. (211 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.831
AEB06613.1
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060:IPR013096:IPR000005; KEGG: clj:CLJU_c13540 putative AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; IMG reference gene:2503575279; PFAM: Cupin domain; Bacterial regulatory helix-turn-helix proteins, AraC family.
  
 
 0.668
AEB06812.1
COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR017963:IPR001126; KEGG: ele:Elen_1465 UMUC domain protein DNA-repair protein; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575487; PFAM: IMS family HHH motif; impB/mucB/samB family.
  
 
 0.668
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.668
AEB07097.1
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.552
AEB07888.1
DNA polymerase III, epsilon subunit; COGs: COG1199 Rad3-related DNA helicase; InterProIPR006055:IPR014001:IPR006555:IPR014013:IPR 013520:IPR006054; KEGG: apv:Apar_1359 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; DEAD-like helicase; helicase c2; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; IMG reference gene:2503576617; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; DnaQ family exonuclease/DinG family helicase, [...]
  
  
 0.533
AEB06723.1
Exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterProIPR014021:IPR001650:IPR001667:IPR003156:IPR 011545:IPR014001:IPR004610; KEGG: apv:Apar_0519 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: Putative uncharacterized protein; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; IMG reference gene:2503575392; PFAM: DHH family; DHHA1 domain; Helicase conserved C-terminal [...]
 
   
 0.486
AEB06952.1
Hypothetical protein; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: dhd:Dhaf_2612 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575632; PFAM: NMT1/THI5 like.
 
   
 0.452
AEB06359.1
KEGG: eel:EUBELI_00139 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575011.
 
   
 0.436
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.423
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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