STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEB06577.1Sulfur carrier protein ThiS; InterPro IPR003749:IPR010035; KEGG: ele:Elen_1749 thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; IMG reference gene:2503575241; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. (65 aa)    
Predicted Functional Partners:
AEB06578.1
Thiamine biosynthesis protein ThiF; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR012729; KEGG: ele:Elen_1748 thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: Thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; IMG reference gene:2503575242; PFAM: ThiF family; TIGRFAM: thiamine biosynthesis protein ThiF, family 2.
  
 0.996
AEB06579.1
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.991
AEB06580.1
COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: ele:Elen_1745 thiamine monophosphate synthase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine monophosphate synthase; IMG reference gene:2503575244; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase.
  
  
 0.790
AEB07327.1
Hydroxymethylpyrimidine synthase; COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: ele:Elen_2064 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; IMG reference gene:2503576032; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC.
  
  
 0.775
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 
 0.722
AEB07330.1
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749; KEGG: ele:Elen_2061 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: Putative uncharacterized protein; TIGRFAM: phosphomethylpyrimidine kinase; IMG reference gene:2503576035; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
  
    0.712
AEB07052.1
Iron-only hydrogenase maturation protein HydG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: ere:EUBREC_0235 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575742; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH.
  
  
 0.650
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.632
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
    0.528
AEB07401.1
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017871:IPR003439:IPR003339:IPR003593; KEGG: bll:BLJ_1432 fused ATP-binding protein and permease of ABC transporter; PFAM: ABC transporter related; cobalt transport protein; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2503576111; PFAM: ABC transporter; Cobalt transport protein.
  
  
 0.501
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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