STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (380 aa)    
Predicted Functional Partners:
tsaD
(SSU ribosomal protein S18P)-alanine acetyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
  
 0.727
AEB07024.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192; KEGG: apv:Apar_0732 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575710; PFAM: Aminotransferase class-V.
 
  
 0.692
AEB06207.1
COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR017969; KEGG: pca:Pcar_2431 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503574851; TIGRFAM: TIGR00268 family protein.
    
 0.685
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR005146:IPR 005147; KEGG: apv:Apar_1054 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Putative uncharacterized protein; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; IMG reference gene:2503576306; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta su [...]
  
  
 0.664
AEB06737.1
COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926:IPR005856:IPR005859; KEGG: shi:Shel_04800 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; IMG reference gene:2503575410; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 0.643
AEB07898.1
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.553
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684:IPR018261; KEGG: ele:Elen_2012 ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; IMG reference gene:2503575656; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
  
 0.531
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.502
AEB06738.1
Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: eel:EUBELI_00637 cysteine desulfurase; PFAM: protein of unknown function UPF0074; SPTR: Putative uncharacterized protein; TIGRFAM: transcriptional regulator, Rrf2 family; IMG reference gene:2503575411; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein.
  
  
 0.497
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
  
 0.468
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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