STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB06737.1COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926:IPR005856:IPR005859; KEGG: shi:Shel_04800 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; IMG reference gene:2503575410; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (312 aa)    
Predicted Functional Partners:
AEB06212.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR018357:IPR001451:IPR005881; KEGG: lsp:Bsph_4643 serine acetyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: serine O-acetyltransferase; IMG reference gene:2503574856; TIGRFAM: serine O-acetyltransferase.
 
 0.995
AEB06929.1
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR006650:IPR000277; KEGG: xce:Xcel_2638 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575609; PFAM: Cys/Met metabolism PLP-dependent enzyme.
 
 
 0.945
AEB06660.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; IMG reference gene:2503575328; PFAM: Aminotransferase class I and II.
  
 0.930
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR002308:IPR015273; KEGG: apv:Apar_1181 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Putative uncharacterized protein; TIGRFAM: cysteinyl-tRNA synthetase; IMG reference gene:2503576194; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.925
AEB06233.1
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: efa:EF3284 cystathionine gamma-synthase, putative; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Putative cystathionine gamma-synthase; IMG reference gene:2503574880; PFAM: Cys/Met metabolism PLP-dependent enzyme.
 
 0.900
AEB06322.1
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: sth:STH2500 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503574970; PFAM: Homocysteine S-methyltransferase.
  
 
 0.863
AEB07027.1
Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
    
 0.829
AEB07209.1
Glutamate--cysteine ligase GCS2; COGs: COG3572 Gamma-glutamylcysteine synthetase; InterPro IPR006336; KEGG: ele:Elen_2348 glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase GCS2; SPTR: Glutamate--cysteine ligase; IMG reference gene:2503575904; PFAM: Glutamate-cysteine ligase family 2(GCS2); TIGRFAM: glutamate--cysteine ligase, plant type.
    
  0.806
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.643
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.629
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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