STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB06754.1Protein of unknown function DUF2179; COGs: COG1284 conserved hypothetical protein; InterPro IPR003740:IPR019264; KEGG: apv:Apar_1288 protein of unknown function DUF161; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: Putative uncharacterized protein; IMG reference gene:2503575427; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179). (299 aa)    
Predicted Functional Partners:
AEB07502.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
    0.882
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
       0.808
prfB
Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
     
 0.793
AEB06751.1
Hypothetical protein; IMG reference gene:2503575424.
       0.512
AEB06898.1
Uncharacterized protein family UPF0029, Impact, N-terminal protein; COGs: COG1739 conserved hypothetical protein; InterPro IPR001498; KEGG: apv:Apar_0903 protein of unknown function UPF0029; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2503575575; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family.
 
    0.458
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.