STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB06778.1COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002306:IPR001412:IPR002305; KEGG: apv:Apar_0653 tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Putative uncharacterized protein; TIGRFAM: tryptophanyl-tRNA synthetase; IMG reference gene:2503575453; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase. (349 aa)    
Predicted Functional Partners:
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR005146:IPR 005147; KEGG: apv:Apar_1054 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Putative uncharacterized protein; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; IMG reference gene:2503576306; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta su [...]
  
  
 0.831
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR001412:IPR002300:IPR013155; KEGG: apv:Apar_0833 leucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Putative uncharacterized protein; TIGRFAM: leucyl-tRNA synthetase; IMG reference gene:2503575845; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family.
 
 
 0.765
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
 
 0.728
argS
COGs: COG0018 Arginyl-tRNA synthetase; InterPro IPR001278:IPR015945:IPR005148:IPR008909; KEGG: apv:Apar_0529 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; IMG reference gene:2503575949; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
  
  
 0.707
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.676
AEB06779.1
COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: lcr:LCRIS_01479 HAD superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: Putative uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2503575454; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB.
  
    0.670
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
  
 
 0.628
AEB06715.1
COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR017926:IPR000728:IPR010918:IPR010141; KEGG: ele:Elen_0262 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Putative uncharacterized protein; TIGRFAM: phosphoribosylformylglycinamidine synthase; IMG reference gene:2503575384; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycin [...]
  
    0.621
thrS
Ser-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
 
  
 0.594
tsaD
(SSU ribosomal protein S18P)-alanine acetyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
  
 0.592
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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