STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (375 aa)    
Predicted Functional Partners:
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
 
 0.998
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 0.997
AEB06874.1
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: apv:Apar_0484 cell cycle protein; PFAM: cell cycle protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575549; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family.
  
 0.992
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.989
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.984
AEB07706.1
Domain of unknown function DUF1727; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR018109:IPR013221:IPR013564; KEGG: blo:BL0430 hypothetical protein; PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503576426; PFAM: Domain of unknown function (DUF1727); Mur ligase middle domain.
  
 0.964
AEB06289.1
UDP-N-acetylmuramyl-tripeptide synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR018109:IPR013221:IPR004101:IPR005761; KEGG: shi:Shel_00220 UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; IMG reference gene:2503574937; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; Belongs to the MurCDEF family. MurE [...]
 
 
 0.930
AEB06870.1
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: apv:Apar_0480 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; SPTR: Putative uncharacterized protein; IMG reference gene:2503575545; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.
 
  
 0.930
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
 0.925
AEB07707.1
COGs: COG3442 glutamine amidotransferase; InterPro IPR017929:IPR011698; KEGG: bln:Blon_0229 CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: CobB/CobQ domain protein glutamine amidotransferase; IMG reference gene:2503576427; PFAM: CobB/CobQ-like glutamine amidotransferase domain.
    
 0.911
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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