STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
AEB06942.1Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR001623:IPR001305:IPR003095:IPR018253:IPR 002939; KEGG: apv:Apar_0797 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; DnaJ central domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575622; PFAM: DnaJ central domain (4 repeats); DnaJ domain. (366 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.985
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.933
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.918
AEB07747.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; KEGG: apv:Apar_1328 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; [...]
   
 
 0.801
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
 
 0.794
AEB07069.1
Regulatory protein MerR; InterPro IPR000551; KEGG: apv:Apar_0754 transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Putative uncharacterized protein; IMG reference gene:2503575759; PFAM: MerR family regulatory protein.
 
 
 0.786
AEB06190.1
COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795:IPR004161:IPR005517:IPR000640:IPR 005225; KEGG: apv:Apar_0059 small GTP-binding protein; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: small GTP-binding protein; IMG reference gene:2503574833; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation [...]
 
 0.774
AEB06408.1
InterPro IPR006058:IPR017900:IPR017896; KEGG: apv:Apar_0185 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575061.
 
 
 0.770
rpsE
SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
 
 
 0.741
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
 
 0.733
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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