STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB06947.1COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: apv:Apar_0792 diacylglycerol kinase; PFAM: diacylglycerol kinase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575627; PFAM: Prokaryotic diacylglycerol kinase. (125 aa)    
Predicted Functional Partners:
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.920
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
    
 0.918
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
 
  0.914
recO
DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.874
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.867
AEB06944.1
RNA modification enzyme, MiaB family; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848:IPR006638:IPR020612:IPR007197:IPR 005839; KEGG: apv:Apar_0795 RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: RNA modification enzyme, MiaB family; IMG reference gene:2503575624; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: radical SAM methylthiotransferase, MiaB/RimO family.
     
 0.642
dnaJ
Heat shock protein DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions [...]
       0.592
AEB06950.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR000103:IPR019575; KEGG: eel:EUBELI_00200 putative glutamate synthase (NADPH) small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Putative uncharacterized protein; IMG reference gene:2503575630; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.519
AEB06951.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR017900:IPR000283:IPR 019574:IPR004108:IPR003149:IPR013352; KEGG: eel:EUBELI_00201 NADH dehydrogenase I chain G; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative uncharacterized protein; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2503575631; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 2Fe-2S iron-sulfur cluster binding do [...]
       0.445
AEB06952.1
Hypothetical protein; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: dhd:Dhaf_2612 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575632; PFAM: NMT1/THI5 like.
       0.445
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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