STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (262 aa)    
Predicted Functional Partners:
queH
Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
      0.890
AEB06723.1
Exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterProIPR014021:IPR001650:IPR001667:IPR003156:IPR 011545:IPR014001:IPR004610; KEGG: apv:Apar_0519 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: Putative uncharacterized protein; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; IMG reference gene:2503575392; PFAM: DHH family; DHHA1 domain; Helicase conserved C-terminal [...]
  
 
 0.869
AEB06134.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.854
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.817
AEB07888.1
DNA polymerase III, epsilon subunit; COGs: COG1199 Rad3-related DNA helicase; InterProIPR006055:IPR014001:IPR006555:IPR014013:IPR 013520:IPR006054; KEGG: apv:Apar_1359 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; DEAD-like helicase; helicase c2; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; IMG reference gene:2503576617; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; DnaQ family exonuclease/DinG family helicase, [...]
  
  
 0.771
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 
 0.756
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
   
 0.747
AEB06985.1
COGs: COG0681 Signal peptidase I; InterPro IPR000223:IPR019759; KEGG: ccu:Ccur_00350 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Putative uncharacterized protein; TIGRFAM: signal peptidase I; IMG reference gene:2503575666; PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
 
  
 0.718
AEB07602.1
COGs: COG0514 Superfamily II DNA helicase; InterProIPR018329:IPR002121:IPR014021:IPR001650:IPR 011545:IPR018982:IPR014001; KEGG: ele:Elen_1066 ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; RQC domain; HRDC domain protein; SMART: helicase domain protein; DEAD-like helicase; HRDC domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: ATP-dependent DNA helicase, RecQ family; IMG reference gene:2503576322; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA [...]
  
 
 0.680
AEB06563.1
KEGG: ele:Elen_2184 hypothetical protein; SPTR: Phosphopantetheine attachment site; IMG reference gene:2503575227; PFAM: Phosphopantetheine attachment site.
  
 
 0.673
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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