STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB07051.1Iron-only hydrogenase maturation protein HydE; COGs: COG0502 Biotin synthase; InterPro IPR005244:IPR006638:IPR007197; KEGG: cth:Cthe_1839 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; IMG reference gene:2503575741; PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE. (365 aa)    
Predicted Functional Partners:
AEB07053.1
Iron-only hydrogenase maturation protein HydF; COGs: COG1160 GTPase; InterPro IPR005225:IPR002917; KEGG: cth:Cthe_0042 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Iron-only hydrogenase maturation protein HydF; TIGRFAM: small GTP-binding protein; IMG reference gene:2503575743; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain.
   
 0.989
AEB06951.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR017900:IPR000283:IPR 019574:IPR004108:IPR003149:IPR013352; KEGG: eel:EUBELI_00201 NADH dehydrogenase I chain G; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative uncharacterized protein; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2503575631; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 2Fe-2S iron-sulfur cluster binding do [...]
 
  
 0.834
AEB07054.1
KEGG: ere:EUBREC_0233 hypothetical protein; SPTR: Hypothetical transcriptional regulatory protein; IMG reference gene:2503575744; TIGRFAM: putative iron-only hydrogenase system regulator.
 
  
 0.821
AEB07052.1
Iron-only hydrogenase maturation protein HydG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: ere:EUBREC_0235 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575742; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH.
 
  
0.818
AEB07311.1
Methyltransferase type 11; InterPro IPR013216; KEGG: ctc:CTC02188 methyltransferase, putative 3-demethylubiquinone-9 3-methyltransferase; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; IMG reference gene:2503576015; PFAM: Methyltransferase domain.
  
  
 0.621
AEB07827.1
COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR000550:IPR006390; KEGG: apv:Apar_0111 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: Putative uncharacterized protein; TIGRFAM: dihydropteroate synthase; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; IMG reference gene:2503576551; PFAM: Pterin binding enzyme; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: dihydropteroate synthase; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
     
 0.577
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.556
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.542
AEB07510.1
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: shi:Shel_22030 ornithine/acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: Putative uncharacterized protein; IMG reference gene:2503576227; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.510
AEB07327.1
Hydroxymethylpyrimidine synthase; COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: ele:Elen_2064 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; IMG reference gene:2503576032; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC.
  
  
 0.487
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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