Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEB07115.1Recombination protein MgsA; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR003959; KEGG: apv:Apar_0452 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2503575805; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus. (462 aa)    
Predicted Functional Partners:
AEB06134.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 
 0.744
AEB06723.1
Exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterProIPR014021:IPR001650:IPR001667:IPR003156:IPR 011545:IPR014001:IPR004610; KEGG: apv:Apar_0519 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: Putative uncharacterized protein; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; IMG reference gene:2503575392; PFAM: DHH family; DHHA1 domain; Helicase conserved C-terminal [...]
  
 
 0.732
AEB07095.1
Cell division protein FtsK/SpoIIIE; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: apv:Apar_0786 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575785; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
  
 0.712
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.622
AEB07114.1
KEGG: apv:Apar_0453 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575804.
       0.609
AEB07602.1
COGs: COG0514 Superfamily II DNA helicase; InterProIPR018329:IPR002121:IPR014021:IPR001650:IPR 011545:IPR018982:IPR014001; KEGG: ele:Elen_1066 ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; RQC domain; HRDC domain protein; SMART: helicase domain protein; DEAD-like helicase; HRDC domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: ATP-dependent DNA helicase, RecQ family; IMG reference gene:2503576322; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA [...]
  
 
 0.567
AEB07111.1
Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: apv:Apar_0456 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; IMG reference gene:2503575801; PFAM: Domain of unknown function DUF20.
       0.562
AEB07112.1
RNA polymerase, sigma 37 subunit, RpsB/SigB; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR014322:IPR014284:IPR000943:IPR000792:IPR 007627:IPR007624:IPR007630; KEGG: apv:Apar_0455 RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SMART: regulatory protein LuxR; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; IMG reference gene:2503575802; PFAM: S [...]
       0.557
AEB07113.1
KEGG: apv:Apar_0454 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575803.
       0.557
AEB07888.1
DNA polymerase III, epsilon subunit; COGs: COG1199 Rad3-related DNA helicase; InterProIPR006055:IPR014001:IPR006555:IPR014013:IPR 013520:IPR006054; KEGG: apv:Apar_1359 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; DEAD-like helicase; helicase c2; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; IMG reference gene:2503576617; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; DnaQ family exonuclease/DinG family helicase, [...]
  
  
 0.486
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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