STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AEB07137.1Dihydroorotate oxidase B, electron transfer subunit; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR012165:IPR006058:IPR001221:IPR001433:IPR 019480:IPR017927; KEGG: apv:Apar_0812 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575827; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD [...] (264 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 0.999
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
 
 0.982
AEB07841.1
Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004:IPR000759; KEGG: apv:Apar_0337 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein; TIGRFAM: glutamate synthase (NADPH), homotetrameric; IMG reference gene:2503576566; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric.
 
 0.969
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.965
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082:IPR006130:IPR006132:IPR006131; KEGG: shi:Shel_11850 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; IMG reference gene:2503575829; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransfe [...]
  
  
 0.854
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
  
 0.826
AEB06950.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR000103:IPR019575; KEGG: eel:EUBELI_00200 putative glutamate synthase (NADPH) small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Putative uncharacterized protein; IMG reference gene:2503575630; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.799
AEB06275.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR017900:IPR013027:IPR017896:IPR000759; KEGG: eel:EUBELI_01295 glutamate synthase (NADPH); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein; IMG reference gene:2503574922; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.771
AEB07747.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; KEGG: apv:Apar_1328 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; [...]
  
  
 0.719
AEB07440.1
Protein of unknown function DUF1667; COGs: COG3862 Uncharacterized protein with conserved CXXC pairs; InterPro IPR013027:IPR000103:IPR012460; KEGG: afn:Acfer_1985 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: protein of unknown function DUF1667; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein; IMG reference gene:2503576150; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Protein of unknown function (DUF1667).
  
 
 0.702
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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