STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigARNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (442 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.986
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.985
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.976
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.972
AEB06161.1
Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR010499; KEGG: dhd:Dhaf_2598 transcriptional regulator, MerR family; PFAM: regulatory protein MerR; transcription activator effector binding; SMART: regulatory protein MerR; SPTR: Transcriptional regulator; IMG reference gene:2503574802; PFAM: MerR family regulatory protein; Bacterial transcription activator, effector binding domain.
  
 
 0.967
AEB06252.1
Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: ctc:CTC01842 putative regulator of efflux transporter; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Transcriptional regulator, MerR family; IMG reference gene:2503574899; PFAM: MerR, DNA binding; MerR family regulatory protein.
  
 
 0.967
AEB06613.1
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060:IPR013096:IPR000005; KEGG: clj:CLJU_c13540 putative AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; IMG reference gene:2503575279; PFAM: Cupin domain; Bacterial regulatory helix-turn-helix proteins, AraC family.
  
 
 0.939
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.917
AEB07251.1
KEGG: apv:Apar_1018 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575950; PFAM: CarD-like/TRCF domain.
   
 
 0.881
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
 
 
 0.837
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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