STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (306 aa)    
Predicted Functional Partners:
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 
 0.969
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 
 
 0.966
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
    
 0.943
AEB06931.1
COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796:IPR012259; KEGG: apv:Apar_0631 dihydrofolate reductase region; PFAM: dihydrofolate reductase region; SPTR: Putative uncharacterized protein; IMG reference gene:2503575611; PFAM: Dihydrofolate reductase.
  
 
 0.939
AEB07184.1
NusB/RsmB/TIM44; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: apv:Apar_0866 NusB/RsmB/TIM44; PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575875; PFAM: NOL1/NOP2/sun family; NusB family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.927
AEB06322.1
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: sth:STH2500 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503574970; PFAM: Homocysteine S-methyltransferase.
    
 0.916
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 0.911
AEB07259.1
COGs: COG0143 Methionyl-tRNA synthetase; InterPro IPR015413; KEGG: apv:Apar_0881 methionine--tRNA ligase; PFAM: tRNA synthetase class I (M); PRIAM: Methionine--tRNA ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575958; PFAM: tRNA synthetases class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 0.911
priA
Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
    0.897
hisS
COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807:IPR006195:IPR002314:IPR004154:IPR 004516; KEGG: apv:Apar_0403 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; IMG reference gene:2503576288; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
 
  
 0.804
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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