STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB07248.1Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347:IPR002198; KEGG: mkm:Mkms_4161 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative uncharacterized protein; IMG reference gene:2503575947; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)    
Predicted Functional Partners:
AEB06676.1
InterPro IPR005181; KEGG: csc:Csac_0206 protein of unknown function DUF303, acetylesterase putative; PFAM: protein of unknown function DUF303 acetylesterase; SPTR: Putative sialate O-acetylesterase; IMG reference gene:2503575345; PFAM: Domain of unknown function (DUF303); Glycosyl hydrolases family 2, sugar binding domain.
  
  
 0.513
AEB07792.1
InterPro IPR005181; KEGG: ppe:PEPE_1762 hypothetical protein; PFAM: protein of unknown function DUF303 acetylesterase; SPTR: Sialate O-acetylesterase; IMG reference gene:2503576514; PFAM: Domain of unknown function (DUF303).
  
  
 0.513
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.510
AEB06561.1
KEGG: ele:Elen_2186 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575225.
  
  
 0.491
AEB07174.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterProIPR012079:IPR000408:IPR018211:IPR015590:IPR 001670; KEGG: eel:EUBELI_02054 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575865; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.452
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.423
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 
   
 0.418
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.