STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB07299.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR016066:IPR005844:IPR005845; KEGG: shi:Shel_23220 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: Phosphomannomutase; IMG reference gene:2503576003; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (588 aa)    
Predicted Functional Partners:
glgC
Nucleotidyl transferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
  
 
 0.935
AEB07180.1
Glucose-1-phosphate adenylyltransferase, GlgD subunit; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR011832; KEGG: apv:Apar_1048 glucose-1-phosphate adenylyltransferase, GlgD subunit; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; IMG reference gene:2503575871; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit.
  
 
 0.935
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: bad:BAD_0231 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2503575489; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
 
 
 0.934
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.929
AEB07452.1
Nucleotidyl transferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR018130:IPR005835; KEGG: apv:Apar_1293 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503576162; PFAM: Nucleotidyl transferase.
 
  
 0.928
AEB07178.1
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.926
AEB07224.1
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.926
AEB07575.1
Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: apv:Apar_0320 ROK family protein; PFAM: ROK family protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503576294; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).
  
 
 0.921
AEB07799.1
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bcl:ABC1731 glucokinase; PFAM: ROK family protein; SPTR: Glucokinase; IMG reference gene:2503576523; PFAM: ROK family.
  
 
 0.921
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.920
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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