STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (423 aa)    
Predicted Functional Partners:
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
 0.999
AEB07510.1
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: shi:Shel_22030 ornithine/acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: Putative uncharacterized protein; IMG reference gene:2503576227; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.997
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.994
AEB06863.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.966
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
  
  
 0.946
AEB06660.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; IMG reference gene:2503575328; PFAM: Aminotransferase class I and II.
  
 
 0.926
AEB06907.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362:IPR006095:IPR006097:IPR006096; KEGG: chl:Chy400_2231 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: Putative uncharacterized protein; IMG reference gene:2503575584; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.911
AEB06916.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362:IPR006095:IPR006097:IPR006096; KEGG: ccu:Ccur_07080 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Glutamate dehydrogenase (NADP); IMG reference gene:2503575595; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.911
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR020557:IPR003031:IPR000362; KEGG: ele:Elen_2338 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Putative uncharacterized protein; TIGRFAM: argininosuccinate lyase; IMG reference gene:2503576013; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
 
  
 0.877
AEB07683.1
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR006132:IPR006131:IPR006130:IPR002292; KEGG: ele:Elen_0676 putrescine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; SPTR: Ornithine carbamoyltransferase; IMG reference gene:2503576403; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoy [...]
  
  
 0.678
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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