STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEB07674.1Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (265 aa)    
Predicted Functional Partners:
AEB07676.1
COGs: COG1882 Pyruvate-formate lyase; InterPro IPR005949:IPR004184:IPR001150; KEGG: apv:Apar_0656 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: formate acetyltransferase; IMG reference gene:2503576396; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1.
  
 0.986
AEB07675.1
Formate C-acetyltransferase glycine radical; COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150:IPR019777; KEGG: apv:Apar_0655 autonomous glycyl radical cofactor GrcA; PFAM: formate C-acetyltransferase glycine radical; SPTR: Putative uncharacterized protein; IMG reference gene:2503576395; PFAM: Glycine radical.
 
  
 0.942
AEB07747.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; KEGG: apv:Apar_1328 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; [...]
     
 0.706
AEB07174.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterProIPR012079:IPR000408:IPR018211:IPR015590:IPR 001670; KEGG: eel:EUBELI_02054 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575865; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.684
AEB06610.1
COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150:IPR004184:IPR019777:IPR010098; KEGG: ect:ECIAI39_3038 putative formate acetyltransferase 2; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Pyruvate formate-lyase; TIGRFAM: pyruvate formate-lyase; IMG reference gene:2503575275; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: pyruvate formate-lyase.
 
  
 0.649
AEB06353.1
COGs: COG1882 Pyruvate-formate lyase; InterPro IPR019777:IPR004184:IPR001150:IPR010098; KEGG: cbe:Cbei_0705 pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Pyruvate formate-lyase; TIGRFAM: pyruvate formate-lyase; IMG reference gene:2503575005; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: pyruvate formate-lyase.
  
  
 0.577
AEB07673.1
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR002178:IPR013011:IPR011608; KEGG: bpu:BPUM_3507 transcription antiterminator BglG; PFAM: PRD domain protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503576393; PFAM: Mga helix-turn-helix domain; HTH domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
  
  
 0.544
AEB06447.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: clj:CLJU_c03830 putative iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Alcohol dehydrogenase, class IV; IMG reference gene:2503575105; PFAM: Iron-containing alcohol dehydrogenase.
  
  
 0.512
AEB06905.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR018211:IPR001670; KEGG: dsy:DSY1101 hypothetical protein; PFAM: iron-containing alcohol dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575582; PFAM: Iron-containing alcohol dehydrogenase.
  
  
 0.512
AEB07373.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: cbt:CLH_3242 NADPH-dependent butanol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2503576083; PFAM: Iron-containing alcohol dehydrogenase.
  
  
 0.512
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.