STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carBCOGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011761:IPR005479:IPR005481:IPR005480:IPR 011607:IPR006275:IPR005483; KEGG: shi:Shel_13230 carbamoyl-phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; IMG reference gene:2503576588; PFAM: Carbamoyl-phosphate synthase L chain, ATP bin [...] (1107 aa)    
Predicted Functional Partners:
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082:IPR006130:IPR006132:IPR006131; KEGG: shi:Shel_11850 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; IMG reference gene:2503575829; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransfe [...]
 
 0.999
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR017926:IPR002474:IPR000991:IPR006274:IPR 001317:IPR011702; KEGG: shi:Shel_13220 carbamoyl-phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, small subunit; IMG reference gene:2503576589; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
 0.999
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.978
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.962
allB
Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
 
 
 0.959
AEB06863.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
 
 0.958
AEB07555.1
COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146; KEGG: ele:Elen_2016 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Putative uncharacterized protein; IMG reference gene:2503576274; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain.
  
 
 0.933
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.922
AEB07518.1
COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: shi:Shel_19890 glutamine synthetase; PFAM: glutamine synthetase catalytic region; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2503576236; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal.
  
 
 0.922
AEB07841.1
Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004:IPR000759; KEGG: apv:Apar_0337 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein; TIGRFAM: glutamate synthase (NADPH), homotetrameric; IMG reference gene:2503576566; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric.
  
 
 0.921
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
Server load: low (30%) [HD]