STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)    
Predicted Functional Partners:
AEB06164.1
COGs: COG0015 Adenylosuccinate lyase; InterProIPR020557:IPR000362:IPR019468:IPR004769:IPR 003031; KEGG: apv:Apar_1351 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Putative uncharacterized protein; TIGRFAM: adenylosuccinate lyase; IMG reference gene:2503574806; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.996
AEB07155.1
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR018529:IPR015875:IPR000644:IPR001093:IPR 001995; KEGG: apv:Apar_0834 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575846; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase.
  
 
 0.979
purH
IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982:IPR002695; KEGG: apv:Apar_1330 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: Putative uncharacterized protein; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; IMG reference g [...]
  
 0.975
AEB06184.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: apv:Apar_0107 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: hypoxanthine phosphoribosyltransferase; IMG reference gene:2503574827; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.953
AEB06715.1
COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR017926:IPR000728:IPR010918:IPR010141; KEGG: ele:Elen_0262 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Putative uncharacterized protein; TIGRFAM: phosphoribosylformylglycinamidine synthase; IMG reference gene:2503575384; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycin [...]
  
  
 0.943
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082:IPR006130:IPR006132:IPR006131; KEGG: shi:Shel_11850 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; IMG reference gene:2503575829; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransfe [...]
  
 
 0.933
AEB06288.1
COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583:IPR001962:IPR006426:IPR017932; KEGG: lsp:Bsph_4225 asparagine synthetase [glutamine-hydrolyzing] 1; PFAM: asparagine synthase; glutamine amidotransferase class-II; SPTR: Putative uncharacterized protein; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); IMG reference gene:2503574936; PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing).
  
 
 0.932
AEB06660.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; IMG reference gene:2503575328; PFAM: Aminotransferase class I and II.
  
 0.929
AEB06839.1
COGs: COG1794 Aspartate racemase; InterPro IPR018187:IPR015942:IPR004380; KEGG: pjd:Pjdr2_3258 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Putative uncharacterized protein; TIGRFAM: aspartate racemase; IMG reference gene:2503575514; PFAM: Asp/Glu/Hydantoin racemase.
    
  0.901
AEB06411.1
Asparaginase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR020827:IPR006034; KEGG: ele:Elen_0759 L-asparaginase, type I; PFAM: Asparaginase/glutaminase; SPTR: Putative uncharacterized protein; IMG reference gene:2503575064; PFAM: Asparaginase.
    
  0.900
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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