STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmN23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (348 aa)    
Predicted Functional Partners:
rimO
SSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
 
  
 0.806
miaB
RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
  
 0.760
AEB06944.1
RNA modification enzyme, MiaB family; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848:IPR006638:IPR020612:IPR007197:IPR 005839; KEGG: apv:Apar_0795 RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: RNA modification enzyme, MiaB family; IMG reference gene:2503575624; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: radical SAM methylthiotransferase, MiaB/RimO family.
 
  
 0.758
AEB06941.1
COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR010723:IPR004559; KEGG: apv:Apar_0799 oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; IMG reference gene:2503575621; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase.
 
   
 0.707
AEB07888.1
DNA polymerase III, epsilon subunit; COGs: COG1199 Rad3-related DNA helicase; InterProIPR006055:IPR014001:IPR006555:IPR014013:IPR 013520:IPR006054; KEGG: apv:Apar_1359 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; DEAD-like helicase; helicase c2; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; IMG reference gene:2503576617; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; DnaQ family exonuclease/DinG family helicase, [...]
  
  
 0.663
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.582
AEB06845.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ttr:Tter_2695 RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575520; PFAM: NOL1/NOP2/sun family.
  
  
 0.581
AEB07184.1
NusB/RsmB/TIM44; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: apv:Apar_0866 NusB/RsmB/TIM44; PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503575875; PFAM: NOL1/NOP2/sun family; NusB family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.581
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
       0.579
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
 
 
 0.577
Your Current Organism:
Coriobacterium glomerans
NCBI taxonomy Id: 700015
Other names: C. glomerans PW2, Coriobacterium glomerans DSM 20642, Coriobacterium glomerans PW2, Coriobacterium glomerans str. PW2, Coriobacterium glomerans strain PW2
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