node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEV96834.1 | AEV96835.1 | Niako_0436 | Niako_0437 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.924 |
AEV96834.1 | AEV96836.1 | Niako_0436 | Niako_0438 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: OHCU decarboxylase; TIGRFAM: OHCU decarboxylase; InterPro IPR017595:IPR018020; KEGG: cpi:Cpin_6772 OHCU decarboxylase; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: OHCU decarboxylase; TIGRFAM:2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline decarboxylase, type 2. | 0.939 |
AEV96834.1 | AEV96837.1 | Niako_0436 | Niako_0439 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: Cupin domain; COGs: COG3257 Uncharacterized protein possibly involved in glyoxylate utilization; InterPro IPR013096; KEGG: cpi:Cpin_6771 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein. | 0.875 |
AEV96834.1 | AEV96838.1 | Niako_0436 | Niako_0440 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | Amidase, hydantoinase/carbamoylase family; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidase, hydantoinase/carbamoylase family; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010158:IPR002933:IPR011650; KEGG: cpi:Cpin_6770 amidase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: Allantoate deiminase; SPTR: Amidase, hydantoinase/carbamoylase family; TIGRFAM: Amidase, hydantoinase/carbamoylase. | 0.784 |
AEV96834.1 | AEV96839.1 | Niako_0436 | Niako_0441 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | Allantoinase; PFAM: Amidohydrolase family; TIGRFAM: allantoinase; dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR017593:IPR006680; KEGG: cpi:Cpin_6769 allantoinase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Allantoinase; TIGRFAM: Allantoinase. | 0.906 |
AEV96834.1 | AEV96840.1 | Niako_0436 | Niako_0442 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | 0.846 |
AEV96834.1 | AEV96850.1 | Niako_0436 | Niako_0452 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | Xanthine dehydrogenase; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; COGs: COG4631 Xanthine dehydrogenase molybdopterin-binding subunit B; InterPro IPR000674:IPR008274; KEGG: cpi:Cpin_6766 xanthine dehydrogenase; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; PRIAM: Xanthine dehydrogenase; SPTR: Xanthine dehydrogenase. | 0.486 |
AEV96834.1 | AEV96851.1 | Niako_0436 | Niako_0453 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | (2Fe-2S)-binding domain-containing protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; [2Fe-2S] binding domain; TIGRFAM: xanthine dehydrogenase, small subunit; COGs: COG4630 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A; InterPro IPR001041:IPR002888:IPR002346:IPR005107; KEGG: cpi:Cpin_6765 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding; Ferredoxin; Molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein, C-terminal; SPTR: (2Fe-2S)-bin [...] | 0.486 |
AEV96834.1 | AEV96855.1 | Niako_0436 | Niako_0457 | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | NCS1 nucleoside transporter family; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; TIGRFAM: NCS1 nucleoside transporter family; COGs: COG1953 Cytosine/uracil/thiamine/allantoin permease; InterPro IPR012681:IPR001248; KEGG: cpi:Cpin_3444 NCS1 nucleoside transporter family; PFAM: Permease, cytosine/purines, uracil, thiamine, allantoin; SPTR: NCS1 nucleoside transporter family; TIGRFAM: Nucleobase cation symporter-1, NCS1; manually curated. | 0.667 |
AEV96835.1 | AEV96834.1 | Niako_0437 | Niako_0436 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.924 |
AEV96835.1 | AEV96836.1 | Niako_0437 | Niako_0438 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | PFAM: OHCU decarboxylase; TIGRFAM: OHCU decarboxylase; InterPro IPR017595:IPR018020; KEGG: cpi:Cpin_6772 OHCU decarboxylase; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: OHCU decarboxylase; TIGRFAM:2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline decarboxylase, type 2. | 0.999 |
AEV96835.1 | AEV96837.1 | Niako_0437 | Niako_0439 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | PFAM: Cupin domain; COGs: COG3257 Uncharacterized protein possibly involved in glyoxylate utilization; InterPro IPR013096; KEGG: cpi:Cpin_6771 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein. | 0.897 |
AEV96835.1 | AEV96838.1 | Niako_0437 | Niako_0440 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Amidase, hydantoinase/carbamoylase family; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidase, hydantoinase/carbamoylase family; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010158:IPR002933:IPR011650; KEGG: cpi:Cpin_6770 amidase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: Allantoate deiminase; SPTR: Amidase, hydantoinase/carbamoylase family; TIGRFAM: Amidase, hydantoinase/carbamoylase. | 0.911 |
AEV96835.1 | AEV96839.1 | Niako_0437 | Niako_0441 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Allantoinase; PFAM: Amidohydrolase family; TIGRFAM: allantoinase; dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR017593:IPR006680; KEGG: cpi:Cpin_6769 allantoinase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Allantoinase; TIGRFAM: Allantoinase. | 0.928 |
AEV96835.1 | AEV96840.1 | Niako_0437 | Niako_0442 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | 0.992 |
AEV96835.1 | AEV96850.1 | Niako_0437 | Niako_0452 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Xanthine dehydrogenase; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; COGs: COG4631 Xanthine dehydrogenase molybdopterin-binding subunit B; InterPro IPR000674:IPR008274; KEGG: cpi:Cpin_6766 xanthine dehydrogenase; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; PRIAM: Xanthine dehydrogenase; SPTR: Xanthine dehydrogenase. | 0.797 |
AEV96835.1 | AEV96851.1 | Niako_0437 | Niako_0453 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | (2Fe-2S)-binding domain-containing protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; [2Fe-2S] binding domain; TIGRFAM: xanthine dehydrogenase, small subunit; COGs: COG4630 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A; InterPro IPR001041:IPR002888:IPR002346:IPR005107; KEGG: cpi:Cpin_6765 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding; Ferredoxin; Molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein, C-terminal; SPTR: (2Fe-2S)-bin [...] | 0.722 |
AEV96835.1 | AEV96855.1 | Niako_0437 | Niako_0457 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | NCS1 nucleoside transporter family; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; TIGRFAM: NCS1 nucleoside transporter family; COGs: COG1953 Cytosine/uracil/thiamine/allantoin permease; InterPro IPR012681:IPR001248; KEGG: cpi:Cpin_3444 NCS1 nucleoside transporter family; PFAM: Permease, cytosine/purines, uracil, thiamine, allantoin; SPTR: NCS1 nucleoside transporter family; TIGRFAM: Nucleobase cation symporter-1, NCS1; manually curated. | 0.633 |
AEV96835.1 | AEV98435.1 | Niako_0437 | Niako_2080 | Hydroxyisourate hydrolase; PFAM: HIUase/Transthyretin family; TIGRFAM: hydroxyisourate hydrolase; COGs: COG2351 Transthyretin-like protein; InterPro IPR000895:IPR014306; KEGG: cpi:Cpin_6773 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; PRIAM: Hydroxyisourate hydrolase; SMART: Transthyretin/hydroxyisourate hydrolase; SPTR: 5-hydroxyisourate hydrolase; TIGRFAM: Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | PFAM: Oxidoreductase molybdopterin binding domain; COGs: COG2041 Sulfite oxidase; InterPro IPR000572; KEGG: cpi:Cpin_2409 oxidoreductase molybdopterin binding; PFAM: Oxidoreductase, molybdopterin binding; SPTR: Oxidoreductase molybdopterin binding. | 0.646 |
AEV96836.1 | AEV96834.1 | Niako_0438 | Niako_0436 | PFAM: OHCU decarboxylase; TIGRFAM: OHCU decarboxylase; InterPro IPR017595:IPR018020; KEGG: cpi:Cpin_6772 OHCU decarboxylase; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: OHCU decarboxylase; TIGRFAM:2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline decarboxylase, type 2. | Hypothetical protein; PFAM: HpcH/HpaI aldolase/citrate lyase family; KEGG: cpi:Cpin_6774 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.939 |