STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
AEV99806.1Transcriptional regulator, Crp/Fnr family; PFAM: Response regulator receiver domain; Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR001789:IPR000595; KEGG: cpi:Cpin_5556 Crp/Fnr family transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Cyclic nucleotide-binding; SMART: Signal transduction response regulator, receiver region; Cyclic nucleotide-binding; SPTR: Transcriptional regulator, Crp/Fnr family. (353 aa)    
Predicted Functional Partners:
AEV98225.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR000014:IPR003661:IPR003594:IPR013767; KEGG: dfe:Dfer_5317 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgro [...]
 
 0.959
AEV97523.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; CHASE3 domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR007891:IPR013767; KEGG: cpi:Cpin_0578 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; CHASE3; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPa [...]
 
 0.958
AEV98303.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR000014:IPR003661:IPR003594:IPR013767; KEGG: cpi:Cpin_5555 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgro [...]
 
 0.958
AEW02418.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655:IPR013767:IPR003661:IPR003594:IPR 001789:IPR008207:IPR000014:IPR001610; KEGG: sli:Slin_3142 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-3; PAS fold; [...]
 
 
0.947
AEW02670.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR013655:IPR013656:IPR003018:IPR 003661:IPR003594:IPR001789:IPR000014:IPR001610; KEGG: swo:Swol_0601 signal transduction histidine kinase-like protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-3; PAS fold; PAS fold-4; GAF; Signal transduction response [...]
  
 
0.938
AEW00247.1
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789; KEGG: cpi:Cpin_0325 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; HAMP linker domain; Signal transduction response regulator, receiver region; SMART: ATP-binding region, AT [...]
  
 
0.936
AEW01502.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR003661:IPR003594:IPR001789; KEGG: dfe:Dfer_2525 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; ATP-binding region [...]
 
 0.917
AEV99073.1
Signal transduction histidine kinase; PFAM: HAMP domain; Nitrate and nitrite sensing; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789:IPR013587; KEGG: chu:CHU_2080 sensor histidine kinase/response regulator fusion protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; Nitrate/nitrite sensing prot [...]
  
 
0.910
AEV96448.1
Integral membrane sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: cpi:Cpin_0578 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, d [...]
 
 0.908
AEW02239.1
Hpt sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: chu:CHU_2895 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) re [...]
 
 0.898
Your Current Organism:
Niastella koreensis
NCBI taxonomy Id: 700598
Other names: N. koreensis GR20-10, Niastella koreensis DSM 17620, Niastella koreensis GR20-10, Niastella koreensis NBRC 106392, Niastella koreensis str. GR20-10, Niastella koreensis strain GR20-10
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