STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEW02296.1PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR010280:IPR001566; KEGG: cpi:Cpin_0862 RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; Deoxyribonuclease/rho motif-related TRAM; SPTR: RNA methyltransferase, TrmA family; TIGRFAM: 23S rRNA methyltransferase/RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (470 aa)    
Predicted Functional Partners:
AEW02295.1
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: pdi:BDI_3603 rhomboid family protein; PFAM: Peptidase S54, rhomboid; SPTR: Rhomboid family protein.
       0.655
AEW00842.1
Fmu (Sun) domain protein; PFAM: NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: cpi:Cpin_6488 Fmu (Sun) domain protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: Fmu (Sun) domain protein.
 
  
 0.645
AEV98365.1
tRNA/rRNA methyltransferase (SpoU); PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537; KEGG: cpi:Cpin_1675 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SPTR: tRNA/rRNA methyltransferase (SpoU); Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.629
AEW02710.1
PFAM: Putative methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; InterPro IPR003358; KEGG: cpi:Cpin_1011 tRNA (guanine-N(7)-)-methyltransferase; PFAM: tRNA (guanine-N-7) methyltransferase; SPTR: tRNA (guanine-N(7)-)-methyltransferase.
 
  
 0.618
AEV97900.1
RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: cpi:Cpin_2929 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase TrmH, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransfer [...]
 
  
 0.562
AEW00915.1
PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: cpi:Cpin_6619 RNA binding S1 domain protein; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: RNA binding S1 domain protein.
  
    0.553
prmA
(LSU ribosomal protein L11P)-lysine N-methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
 
   
 0.510
AEW00695.1
tRNA/rRNA methyltransferase (SpoU); PFAM: SpoU rRNA Methylase family; COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: cpi:Cpin_1901 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: tRNA/rRNA methyltransferase (SpoU).
 
  
 0.509
AEW01283.1
Fmu (Sun) domain protein; PFAM: NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: cpi:Cpin_6838 Fmu (Sun) domain protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.500
AEW02293.1
PFAM: Endonuclease/Exonuclease/phosphatase family; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: cpi:Cpin_0858 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase.
     
 0.500
Your Current Organism:
Niastella koreensis
NCBI taxonomy Id: 700598
Other names: N. koreensis GR20-10, Niastella koreensis DSM 17620, Niastella koreensis GR20-10, Niastella koreensis NBRC 106392, Niastella koreensis str. GR20-10, Niastella koreensis strain GR20-10
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.