STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEW02836.1PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: mar:MAE_01980 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (460 aa)    
Predicted Functional Partners:
AEV98635.1
Acetate--CoA ligase; PFAM: AMP-binding enzyme; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dps:DP2097 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: Probable acetyl-CoA synthetase.
  
 0.936
AEW02886.1
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.936
AEV98640.1
PFAM: Alcohol dehydrogenase GroES-like domain; TIGRFAM: zinc-binding alcohol dehydrogenase family protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154:IPR014187; KEGG: cyn:Cyan7425_3850 zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase GroES-like; SPTR: Zinc-binding alcohol dehydrogenase family protein; TIGRFAM: Alcohol dehydrogenase, zinc-binding type 2.
  
 
 0.920
AEV96853.1
Methylmalonate-semialdehyde dehydrogenase (acylating); PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR010061:IPR015590; KEGG: cpi:Cpin_3442 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Methylmalonate-semialdehyde dehydrogenase (acylating); SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: Methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.918
AEW02382.1
PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: gau:GAU_0672 putative oxidoreductase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; SPTR: Putative oxidoreductase.
  
 
 0.915
AEV97886.1
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: cpi:Cpin_3681 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: L-aminoadipate-semialdehyde dehydrogenase; SPTR: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.913
AEV96857.1
Beta-ureidopropionase; PFAM: Carbon-nitrogen hydrolase; COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: cpi:Cpin_3446 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: Beta-ureidopropionase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
   
 0.911
AEV98801.1
PFAM: Aldo/keto reductase family; COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395; KEGG: bpy:Bphyt_1700 aldehyde reductase; PFAM: Aldo/keto reductase; PRIAM: Aldehyde reductase; SPTR: Aldehyde reductase; manually curated.
   
 0.911
AEW00748.1
PFAM: Acylphosphatase; COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: rxy:Rxyl_0794 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase.
    
 0.908
AEV96854.1
Acetylornithine transaminase; PFAM: Aminotransferase class-III; COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814; KEGG: cpi:Cpin_3443 aminotransferase class-III; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.907
Your Current Organism:
Niastella koreensis
NCBI taxonomy Id: 700598
Other names: N. koreensis GR20-10, Niastella koreensis DSM 17620, Niastella koreensis GR20-10, Niastella koreensis NBRC 106392, Niastella koreensis str. GR20-10, Niastella koreensis strain GR20-10
Server load: low (18%) [HD]