STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (310 aa)    
Predicted Functional Partners:
hldE
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
 
 0.979
ADO46400.1
KEGG: enc:ECL_00139 ADP-heptose:LPS heptosyltransferase II; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9.
 
  
 0.973
ADO46398.1
KEGG: ent:Ent638_0114 lipopolysaccharide heptosyltransferase III, putative; TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9.
 
  
 0.932
ADO46399.1
Lipopolysaccharide heptosyltransferase I; KEGG: ent:Ent638_0115 ADP-heptose:LPS heptosyl transferase I; TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9.
 
  
 0.926
ADO46397.1
PFAM: glycosyl transferase group 1; KEGG: ent:Ent638_0113 glycosyl transferase, group 1.
 
  
 0.862
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
 
  
 0.800
ADO49777.1
KEGG: kpu:KP1_1061 D,D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Haloacid dehalogenase domain protein hydrolase.
 
  
 0.757
diaA
Sugar isomerase (SIS); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.
 
  
 0.756
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.713
rpsN
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
   
  0.712
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.