STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ghrBD-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. (323 aa)    
Predicted Functional Partners:
ADO49744.1
TIGRFAM: 2-hydroxy-3-oxopropionate reductase; KEGG: 3-hydroxyisobutyrate dehydrogenase GhbD; PFAM: 6-phosphogluconate dehydrogenase NAD-binding.
 
  
 0.924
ghrA
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
 
  
 
0.920
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
  0.918
ADO49743.1
TIGRFAM: hydroxypyruvate isomerase; KEGG: regulatory protein GclR; PFAM: Xylose isomerase domain-containing protein TIM barrel; Belongs to the hyi family.
  
 
 0.917
ADO46442.1
Gluconolactonase; KEGG: spe:Spro_3932 gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region-containing protein.
  
 
 0.913
ADO50384.1
TIGRFAM: malate synthase A; KEGG: cko:CKO_03906 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
   
 
 0.911
ADO48432.1
TIGRFAM: lactoylglutathione lyase; KEGG: gloA; lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
   
 0.910
ADO47553.1
TIGRFAM: glycerate kinase; KEGG: stt:t0367 hypothetical protein; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.908
ADO49745.1
TIGRFAM: glycerate kinase; KEGG: glycerate kinase GclK; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.908
ADO49742.1
KEGG: glycoxylate carboligase GclA; TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; Belongs to the TPP enzyme family.
    
 0.906
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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