Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO46712.1PFAM: protein of unknown function DUF1488; KEGG: ecz:ECS88_3668 hypothetical protein. (85 aa)    
Predicted Functional Partners:
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.951
ADO46709.1
PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: kva:Kvar_0420 DNA topoisomerase type IA zn finger domain protein.
     
 0.886
tsaC
SUA5/yciO/yrdC domain protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
  
  
 0.867
ADO46707.1
KEGG: ecs:ECs4151 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein.
       0.783
smg
PFAM: protein of unknown function DUF494; KEGG: ent:Ent638_3716 hypothetical protein; Belongs to the Smg family.
       0.783
ADO50643.1
PFAM: ATP synthase I chain; KEGG: kva:Kvar_5075 ATP synthase I chain.
  
     0.747
thiK
Thiamine kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
  
     0.652
ADO50372.1
KEGG: cro:ROD_37231 putative lipoprotein.
  
     0.618
ADO49646.1
PFAM: Nucleoside-specific channel-forming protein, Tsx-like; KEGG: kva:Kvar_4018 nucleoside-specific channel-forming protein, Tsx-like protein.
  
     0.570
ADO48237.1
PFAM: protein of unknown function UPF0181; KEGG: sdy:SDY_1717 hypothetical protein; Belongs to the UPF0181 family.
  
     0.566
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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