| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46765.1 | ADO47202.1 | Entcl_0487 | Entcl_0930 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | 0.988 |
| ADO46765.1 | ADO47333.1 | Entcl_0487 | Entcl_1061 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Hpt sensor hybrid histidine kinase; KEGG: cko:CKO_04368 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3. | 0.986 |
| ADO46765.1 | ADO47631.1 | Entcl_0487 | Entcl_1366 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ppg:PputGB1_4400 diguanylate cyclase; SMART: GGDEF domain containing protein. | 0.963 |
| ADO46765.1 | ADO47715.1 | Entcl_0487 | Entcl_1454 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | KEGG: cko:CKO_00521 hypothetical protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver. | 0.971 |
| ADO46765.1 | ADO48167.1 | Entcl_0487 | Entcl_1911 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | KEGG: cro:ROD_19301 chemotaxis protein CheY; PFAM: response regulator receiver; SMART: response regulator receiver. | 0.967 |
| ADO46765.1 | ADO48828.1 | Entcl_0487 | Entcl_2578 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; KEGG: kpu:KP1_2376 hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver. | 0.987 |
| ADO46765.1 | ADO49959.1 | Entcl_0487 | Entcl_3718 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Two component transcriptional regulator, winged helix family; KEGG: enc:ECL_00811 two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver. | 0.984 |
| ADO46765.1 | ADO50312.1 | Entcl_0487 | Entcl_4079 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | KEGG: ent:Ent638_0290 integral membrane sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver. | 0.966 |
| ADO46765.1 | rcsC | Entcl_0487 | Entcl_1499 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. | 0.979 |
| ADO46765.1 | rssB | Entcl_0487 | Entcl_2068 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Response regulator receiver protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.968 |
| ADO47202.1 | ADO46765.1 | Entcl_0930 | Entcl_0487 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | 0.988 |
| ADO47202.1 | ADO47333.1 | Entcl_0930 | Entcl_1061 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | Hpt sensor hybrid histidine kinase; KEGG: cko:CKO_04368 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3. | 0.977 |
| ADO47202.1 | ADO47631.1 | Entcl_0930 | Entcl_1366 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ppg:PputGB1_4400 diguanylate cyclase; SMART: GGDEF domain containing protein. | 0.967 |
| ADO47202.1 | ADO47715.1 | Entcl_0930 | Entcl_1454 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | KEGG: cko:CKO_00521 hypothetical protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver. | 0.944 |
| ADO47202.1 | ADO48167.1 | Entcl_0930 | Entcl_1911 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | KEGG: cro:ROD_19301 chemotaxis protein CheY; PFAM: response regulator receiver; SMART: response regulator receiver. | 0.761 |
| ADO47202.1 | ADO48828.1 | Entcl_0930 | Entcl_2578 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; KEGG: kpu:KP1_2376 hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver. | 0.984 |
| ADO47202.1 | ADO49959.1 | Entcl_0930 | Entcl_3718 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | Two component transcriptional regulator, winged helix family; KEGG: enc:ECL_00811 two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver. | 0.894 |
| ADO47202.1 | ADO50312.1 | Entcl_0930 | Entcl_4079 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | KEGG: ent:Ent638_0290 integral membrane sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver. | 0.968 |
| ADO47202.1 | rcsC | Entcl_0930 | Entcl_1499 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | Histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. | 0.968 |
| ADO47202.1 | rssB | Entcl_0930 | Entcl_2068 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | Response regulator receiver protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.755 |