| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46858.1 | ADO46861.1 | Entcl_0581 | Entcl_0584 | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | TIGRFAM: formate acetyltransferase; KEGG: ecm:EcSMS35_3410 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. | 0.892 |
| ADO46858.1 | ADO46862.1 | Entcl_0581 | Entcl_0585 | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | 0.657 |
| ADO46858.1 | ADO46863.1 | Entcl_0581 | Entcl_0586 | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | TIGRFAM: L-serine dehydratase 1; KEGG: cko:CKO_04512 hypothetical protein; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.936 |
| ADO46858.1 | tdcC | Entcl_0581 | Entcl_0582 | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Serine transporter; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. | 0.754 |
| ADO46858.1 | tdcD | Entcl_0581 | Entcl_0583 | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Acetate kinase; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. | 0.592 |
| ADO46861.1 | ADO46858.1 | Entcl_0584 | Entcl_0581 | TIGRFAM: formate acetyltransferase; KEGG: ecm:EcSMS35_3410 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.892 |
| ADO46861.1 | ADO46862.1 | Entcl_0584 | Entcl_0585 | TIGRFAM: formate acetyltransferase; KEGG: ecm:EcSMS35_3410 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | 0.777 |
| ADO46861.1 | ADO46863.1 | Entcl_0584 | Entcl_0586 | TIGRFAM: formate acetyltransferase; KEGG: ecm:EcSMS35_3410 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. | TIGRFAM: L-serine dehydratase 1; KEGG: cko:CKO_04512 hypothetical protein; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.573 |
| ADO46861.1 | tdcC | Entcl_0584 | Entcl_0582 | TIGRFAM: formate acetyltransferase; KEGG: ecm:EcSMS35_3410 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. | Serine transporter; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. | 0.569 |
| ADO46861.1 | tdcD | Entcl_0584 | Entcl_0583 | TIGRFAM: formate acetyltransferase; KEGG: ecm:EcSMS35_3410 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. | Acetate kinase; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. | 0.756 |
| ADO46862.1 | ADO46858.1 | Entcl_0585 | Entcl_0581 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.657 |
| ADO46862.1 | ADO46861.1 | Entcl_0585 | Entcl_0584 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | TIGRFAM: formate acetyltransferase; KEGG: ecm:EcSMS35_3410 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical. | 0.777 |
| ADO46862.1 | ADO46863.1 | Entcl_0585 | Entcl_0586 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | TIGRFAM: L-serine dehydratase 1; KEGG: cko:CKO_04512 hypothetical protein; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.575 |
| ADO46862.1 | ADO47103.1 | Entcl_0585 | Entcl_0829 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.419 |
| ADO46862.1 | nnrE | Entcl_0585 | Entcl_3991 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.430 |
| ADO46862.1 | pyrB | Entcl_0585 | Entcl_3905 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | TIGRFAM: aspartate carbamoyltransferase; KEGG: kpu:KP1_0536 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.403 |
| ADO46862.1 | pyrI | Entcl_0585 | Entcl_3906 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.409 |
| ADO46862.1 | tdcC | Entcl_0585 | Entcl_0582 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Serine transporter; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. | 0.519 |
| ADO46862.1 | tdcD | Entcl_0585 | Entcl_0583 | Endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 hypothetical protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Acetate kinase; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. | 0.701 |
| ADO46863.1 | ADO46858.1 | Entcl_0586 | Entcl_0581 | TIGRFAM: L-serine dehydratase 1; KEGG: cko:CKO_04512 hypothetical protein; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Pyridoxal-5'-phosphate-dependent protein beta subunit; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.936 |
