Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADO46890.1Transcriptional regulator, DeoR family; PFAM: sugar-binding domain-containing protein; KEGG: kva:Kvar_0592 transcriptional regulator, DeoR family. (323 aa)    
Predicted Functional Partners:
ADO46894.1
KEGG: enc:ECL_04479 AI-2 transport system substrate-binding protein.
 
  
 0.949
lsrK
Carbohydrate kinase, FGGY-like protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
 
  
 0.941
lsrG
Antibiotic biosynthesis monooxygenase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.
 
  
 0.906
lsrF
Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family.
 
  
 0.901
ADO46893.1
PFAM: inner-membrane translocator; KEGG: ent:Ent638_3534 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.860
ADO46892.1
PFAM: inner-membrane translocator; KEGG: kpu:KP1_4803 putative ABC transport system permease component.
 
  
 0.665
ADO46891.1
KEGG: kpe:KPK_0605 autoinducer-2 ABC transporter, ATP-binding protein LsrA; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.592
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
   
 0.490
ADO46437.1
PFAM: Carbohydrate kinase, FGGY-like; KEGG: cko:CKO_05037 hypothetical protein.
 
  
 0.468
ADO47474.1
KEGG: cro:ROD_24811 ABC transporter, substrate-binding protein.
 
  
 0.433
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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