STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO46890.1Transcriptional regulator, DeoR family; PFAM: sugar-binding domain-containing protein; KEGG: kva:Kvar_0592 transcriptional regulator, DeoR family. (323 aa)    
Predicted Functional Partners:
ADO46894.1
KEGG: enc:ECL_04479 AI-2 transport system substrate-binding protein.
 
  
 0.922
lsrK
Carbohydrate kinase, FGGY-like protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
 
  
 0.916
lsrF
Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family.
 
  
 0.866
lsrG
Antibiotic biosynthesis monooxygenase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.
 
  
 0.856
ADO46893.1
PFAM: inner-membrane translocator; KEGG: ent:Ent638_3534 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.811
ADO46892.1
PFAM: inner-membrane translocator; KEGG: kpu:KP1_4803 putative ABC transport system permease component.
 
  
 0.653
ADO46891.1
KEGG: kpe:KPK_0605 autoinducer-2 ABC transporter, ATP-binding protein LsrA; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.562
ADO49700.1
TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; KEGG: kpe:KPK_0616 dihydroxyacetone kinase subunit M; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; PEP-utilising protein domain protein; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family.
 
  
 0.481
ADO46437.1
PFAM: Carbohydrate kinase, FGGY-like; KEGG: cko:CKO_05037 hypothetical protein.
 
  
 0.429
ADO46888.1
PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: enc:ECL_04485 2,4-dienoyl-CoA reductase.
       0.426
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.