Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO46893.1PFAM: inner-membrane translocator; KEGG: ent:Ent638_3534 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (327 aa)    
Predicted Functional Partners:
ADO46894.1
KEGG: enc:ECL_04479 AI-2 transport system substrate-binding protein.
 0.998
ADO46891.1
KEGG: kpe:KPK_0605 autoinducer-2 ABC transporter, ATP-binding protein LsrA; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.992
lsrG
Antibiotic biosynthesis monooxygenase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.
 
  
 0.974
lsrF
Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family.
 
  
 0.973
ADO46892.1
PFAM: inner-membrane translocator; KEGG: kpu:KP1_4803 putative ABC transport system permease component.
 
 
0.970
lsrK
Carbohydrate kinase, FGGY-like protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
 
  
 0.893
ADO46890.1
Transcriptional regulator, DeoR family; PFAM: sugar-binding domain-containing protein; KEGG: kva:Kvar_0592 transcriptional regulator, DeoR family.
 
  
 0.860
ADO49629.1
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: cro:ROD_28431 putative ABC transporter periplasmic binding protein.
 
 
 0.851
rbsA-3
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
 
 0.837
ADO47474.1
KEGG: cro:ROD_24811 ABC transporter, substrate-binding protein.
 
 0.832
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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