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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO46894.1KEGG: enc:ECL_04479 AI-2 transport system substrate-binding protein. (333 aa)    
Predicted Functional Partners:
ADO46893.1
PFAM: inner-membrane translocator; KEGG: ent:Ent638_3534 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 0.997
ADO46892.1
PFAM: inner-membrane translocator; KEGG: kpu:KP1_4803 putative ABC transport system permease component.
 0.994
ADO46891.1
KEGG: kpe:KPK_0605 autoinducer-2 ABC transporter, ATP-binding protein LsrA; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.987
lsrF
Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family.
 
  
 0.987
lsrG
Antibiotic biosynthesis monooxygenase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.
 
  
 0.986
lsrK
Carbohydrate kinase, FGGY-like protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
 
  
 0.927
ADO46890.1
Transcriptional regulator, DeoR family; PFAM: sugar-binding domain-containing protein; KEGG: kva:Kvar_0592 transcriptional regulator, DeoR family.
 
  
 0.922
ADO47202.1
KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein.
   
 
 0.804
ADO47333.1
Hpt sensor hybrid histidine kinase; KEGG: cko:CKO_04368 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3.
  
 
 0.789
ADO48828.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; KEGG: kpu:KP1_2376 hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver.
   
 
 0.789
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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