Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADO46948.1KEGG: seg:SG0292 hypothetical protein. (505 aa)    
Predicted Functional Partners:
ADO46949.1
KEGG: seg:SG0293 hypothetical protein.
 
  
 0.665
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 
 0.645
ADO46351.1
KEGG: eoh:ECO103_0297 hypothetical protein.
  
     0.640
ADO46947.1
PFAM: Prophage CP4-57 regulatory; KEGG: dze:Dd1591_0922 phage transcriptional regulator, AlpA.
       0.596
ADO48097.1
KEGG: enc:ECL_01666 DNA replication protein DnaC.
  
 
 0.538
ADO50011.1
SMART: AAA ATPase; KEGG: sec:SC4395 DNA replication protein DnaC.
  
 
 0.538
ADO47366.1
KEGG: ebw:BWG_2381 CP4-57 prophage; DNA-binding transcriptional activator; manually curated; PFAM: Prophage CP4-57 regulatory.
 
     0.504
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.495
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.475
ADO47364.1
KEGG: seg:SG0293 hypothetical protein.
 
  
 0.453
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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