STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
hldErfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (477 aa)    
Predicted Functional Partners:
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.989
ADO49777.1
KEGG: kpu:KP1_1061 D,D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Haloacid dehalogenase domain protein hydrolase.
  
 0.986
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
 
 0.979
ADO46400.1
KEGG: enc:ECL_00139 ADP-heptose:LPS heptosyltransferase II; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9.
 
  
 0.863
diaA
Sugar isomerase (SIS); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.
   
 0.862
ADO46398.1
KEGG: ent:Ent638_0114 lipopolysaccharide heptosyltransferase III, putative; TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9.
 
  
 0.808
ADO46399.1
Lipopolysaccharide heptosyltransferase I; KEGG: ent:Ent638_0115 ADP-heptose:LPS heptosyl transferase I; TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9.
 
  
 0.763
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
       0.674
ADO46777.1
TIGRFAM: KpsF/GutQ family protein; KEGG: enc:ECL_04579 D-arabinose 5-phosphate isomerase; PFAM: sugar isomerase (SIS); CBS domain containing protein.
 
   
 0.660
ADO46980.1
PFAM: adenylate cyclase; KEGG: kpu:KP1_4744 hypothetical protein.
       0.632
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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