Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADO46992.1KEGG: kpu:KP1_4730 outer membrane channel protein; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein. (493 aa)    
Predicted Functional Partners:
ADO49572.1
Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: kva:Kvar_3937 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.993
ADO49159.1
KEGG: kpu:KP1_1879 macrolide transporter subunit MacA; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.980
ADO49573.1
Manually curated; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: kva:Kvar_3938 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.
 
 0.948
ADO47825.1
KEGG: kpn:KPN_02576 multidrug resistance outer membrane protein MdtQ; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein.
     
 0.914
ADO47310.1
KEGG: enc:ECL_04022 efflux pump membrane protein; TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein.
 
 
 0.870
macB
ABC transporter related protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.863
ADO48282.1
KEGG: reu:Reut_A3424 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.829
ADO49191.1
KEGG: enc:ECL_02806 putative lipoprotein.
    
   0.819
mdtA
Manually curated; TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: ecv:APECO1_1164 multidrug efflux system subunit MdtA; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.818
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
 
 
 0.808
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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