| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46281.1 | ADO47069.1 | Entcl_0002 | Entcl_0794 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.865 |
| ADO46281.1 | ADO47765.1 | Entcl_0002 | Entcl_1504 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; KEGG: ecc:c2754 ADA regulatory protein; SMART: Helix-turn-helix, AraC domain. | 0.435 |
| ADO46281.1 | ADO48838.1 | Entcl_0002 | Entcl_2588 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Manually curated; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; KEGG: efe:EFER_1316 exonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. | 0.883 |
| ADO46281.1 | mutL | Entcl_0002 | Entcl_3988 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.959 |
| ADO46281.1 | polA | Entcl_0002 | Entcl_4391 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.989 |
| ADO47068.1 | ADO47069.1 | Entcl_0793 | Entcl_0794 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.785 |
| ADO47068.1 | mltC | Entcl_0793 | Entcl_0792 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.764 |
| ADO47068.1 | trmB | Entcl_0793 | Entcl_0795 | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.607 |
| ADO47069.1 | ADO46281.1 | Entcl_0794 | Entcl_0002 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.865 |
| ADO47069.1 | ADO47068.1 | Entcl_0794 | Entcl_0793 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.785 |
| ADO47069.1 | ADO47765.1 | Entcl_0794 | Entcl_1504 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; KEGG: ecc:c2754 ADA regulatory protein; SMART: Helix-turn-helix, AraC domain. | 0.583 |
| ADO47069.1 | ADO48838.1 | Entcl_0794 | Entcl_2588 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Manually curated; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; KEGG: efe:EFER_1316 exonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. | 0.868 |
| ADO47069.1 | mltC | Entcl_0794 | Entcl_0792 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.678 |
| ADO47069.1 | mutL | Entcl_0794 | Entcl_3988 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.652 |
| ADO47069.1 | mutM | Entcl_0794 | Entcl_0113 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.588 |
| ADO47069.1 | polA | Entcl_0794 | Entcl_4391 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.604 |
| ADO47069.1 | sfsA | Entcl_0794 | Entcl_3588 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | KEGG: set:SEN0192 sugar fermentation stimulation protein A; TIGRFAM: sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; Belongs to the SfsA family. | 0.895 |
| ADO47069.1 | trmB | Entcl_0794 | Entcl_0795 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.655 |
| ADO47765.1 | ADO46281.1 | Entcl_1504 | Entcl_0002 | Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; KEGG: ecc:c2754 ADA regulatory protein; SMART: Helix-turn-helix, AraC domain. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.435 |
| ADO47765.1 | ADO47069.1 | Entcl_1504 | Entcl_0794 | Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; KEGG: ecc:c2754 ADA regulatory protein; SMART: Helix-turn-helix, AraC domain. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.583 |
