| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO47075.1 | ADO47076.1 | Entcl_0800 | Entcl_0801 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.930 |
| ADO47075.1 | ADO47077.1 | Entcl_0800 | Entcl_0802 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | 0.862 |
| ADO47075.1 | ADO47078.1 | Entcl_0800 | Entcl_0803 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | 0.836 |
| ADO47075.1 | ADO47079.1 | Entcl_0800 | Entcl_0804 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.858 |
| ADO47075.1 | ADO47080.1 | Entcl_0800 | Entcl_0805 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | KEGG: kpe:KPK_0725 twitching motility family protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E. | 0.657 |
| ADO47076.1 | ADO47075.1 | Entcl_0801 | Entcl_0800 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.930 |
| ADO47076.1 | ADO47077.1 | Entcl_0801 | Entcl_0802 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | 0.835 |
| ADO47076.1 | ADO47078.1 | Entcl_0801 | Entcl_0803 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | 0.846 |
| ADO47076.1 | ADO47079.1 | Entcl_0801 | Entcl_0804 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.858 |
| ADO47076.1 | ADO47080.1 | Entcl_0801 | Entcl_0805 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: kpe:KPK_0725 twitching motility family protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E. | 0.677 |
| ADO47077.1 | ADO47075.1 | Entcl_0802 | Entcl_0800 | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.862 |
| ADO47077.1 | ADO47076.1 | Entcl_0802 | Entcl_0801 | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.835 |
| ADO47077.1 | ADO47078.1 | Entcl_0802 | Entcl_0803 | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | 0.875 |
| ADO47077.1 | ADO47079.1 | Entcl_0802 | Entcl_0804 | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.858 |
| ADO47077.1 | ADO47080.1 | Entcl_0802 | Entcl_0805 | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | KEGG: kpe:KPK_0725 twitching motility family protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E. | 0.657 |
| ADO47078.1 | ADO47075.1 | Entcl_0803 | Entcl_0800 | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.836 |
| ADO47078.1 | ADO47076.1 | Entcl_0803 | Entcl_0801 | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.846 |
| ADO47078.1 | ADO47077.1 | Entcl_0803 | Entcl_0802 | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | PFAM: protein of unknown function DUF167; KEGG: kpu:KP1_4664 hypothetical protein; Belongs to the UPF0235 family. | 0.875 |
| ADO47078.1 | ADO47079.1 | Entcl_0803 | Entcl_0804 | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.936 |
| ADO47078.1 | ADO47080.1 | Entcl_0803 | Entcl_0805 | PFAM: protein of unknown function YGGT; KEGG: kpn:KPN_03386 hypothetical protein. | KEGG: kpe:KPK_0725 twitching motility family protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E. | 0.657 |