STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
glaHProtein of unknown function CsiD; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (325 aa)    
Predicted Functional Partners:
lhgD
FAD dependent oxidoreductase; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2HGDH family.
 
 
 0.998
ADO47148.1
KEGG: cko:CKO_04008 succinate-semialdehyde dehydrogenase I; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.975
ADO49058.1
KEGG: kva:Kvar_3367 succinic semialdehyde dehydrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.933
ADO48366.1
PFAM: FAD linked oxidase domain protein; KEGG: ent:Ent638_1747 FAD linked oxidase domain-containing protein.
  
  
  0.914
ADO47150.1
KEGG: kpu:KP1_1099 DNA-binding transcriptional regulator CsiR; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
 
   
 0.744
ADO50321.1
Manually curated; PFAM: Sel1 domain protein repeat-containing protein; KEGG: enc:ECL_00332 Sel1 domain-containing protein; SMART: Sel1 domain protein repeat-containing protein.
  
     0.640
ADO50067.1
PFAM: protein of unknown function DUF1398; KEGG: sec:SC1853 putative cytoplasmic protein.
  
     0.536
ADO47621.1
PFAM: Cl- channel voltage-gated family protein; KEGG: kpu:KP1_3991 hypothetical protein.
  
     0.534
ADO47149.1
GABA permease; KEGG: set:SEN2637 gamma-aminobutyrate transporter; TIGRFAM: GABA permease; PFAM: amino acid permease-associated region.
  
  
 0.520
ADO47726.1
KEGG: enc:ECL_03608 putative tricarboxylic transport membrane protein.
 
   
 0.515
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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