| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO47171.1 | ADO47173.1 | Entcl_0899 | Entcl_0901 | Hypothetical protein. | PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; GAF domain protein; PEP-utilising protein mobile region; KEGG: cro:ROD_28711 phosphoenolpyruvate-protein phosphotransferase (PTS system, enzyme I); SMART: GAF domain protein; Belongs to the PEP-utilizing enzyme family. | 0.746 |
| ADO47171.1 | rppH | Entcl_0899 | Entcl_0900 | Hypothetical protein. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.773 |
| ADO47173.1 | ADO47171.1 | Entcl_0901 | Entcl_0899 | PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; GAF domain protein; PEP-utilising protein mobile region; KEGG: cro:ROD_28711 phosphoenolpyruvate-protein phosphotransferase (PTS system, enzyme I); SMART: GAF domain protein; Belongs to the PEP-utilizing enzyme family. | Hypothetical protein. | 0.746 |
| ADO47173.1 | rppH | Entcl_0901 | Entcl_0900 | PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; GAF domain protein; PEP-utilising protein mobile region; KEGG: cro:ROD_28711 phosphoenolpyruvate-protein phosphotransferase (PTS system, enzyme I); SMART: GAF domain protein; Belongs to the PEP-utilizing enzyme family. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.838 |
| ADO48770.1 | dnaX | Entcl_2520 | Entcl_3320 | Pseudouridine synthase; KEGG: sbo:SBO_1797 23S rRNA pseudouridylate synthase B; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.464 |
| ADO48770.1 | rppH | Entcl_2520 | Entcl_0900 | Pseudouridine synthase; KEGG: sbo:SBO_1797 23S rRNA pseudouridylate synthase B; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.582 |
| ADO48770.1 | ybeY | Entcl_2520 | Entcl_3146 | Pseudouridine synthase; KEGG: sbo:SBO_1797 23S rRNA pseudouridylate synthase B; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.421 |
| apaH | rnr | Entcl_3674 | Entcl_3979 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.407 |
| apaH | rppH | Entcl_3674 | Entcl_0900 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.605 |
| apaH | ybeY | Entcl_3674 | Entcl_3146 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.410 |
| dapF | rppH | Entcl_4226 | Entcl_0900 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.911 |
| dnaX | ADO48770.1 | Entcl_3320 | Entcl_2520 | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Pseudouridine synthase; KEGG: sbo:SBO_1797 23S rRNA pseudouridylate synthase B; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. | 0.464 |
| dnaX | rppH | Entcl_3320 | Entcl_0900 | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.589 |
| hfq | rnr | Entcl_3986 | Entcl_3979 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.761 |
| hfq | rpoZ | Entcl_3986 | Entcl_0100 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.408 |
| hfq | rppH | Entcl_3986 | Entcl_0900 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.658 |
| hfq | ybeY | Entcl_3986 | Entcl_3146 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.549 |
| rnr | apaH | Entcl_3979 | Entcl_3674 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.407 |
| rnr | hfq | Entcl_3979 | Entcl_3986 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.761 |
| rnr | rppH | Entcl_3979 | Entcl_0900 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.597 |