| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46653.1 | rlmD | Entcl_0375 | Entcl_0931 | KEGG: cko:CKO_04760 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; Valyl-tRNA synthetase, class Ia, tRNA binding arm; SMART: AAA ATPase. | RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.465 |
| ADO47202.1 | ADO47204.1 | Entcl_0930 | Entcl_0932 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.776 |
| ADO47202.1 | ADO47205.1 | Entcl_0930 | Entcl_0933 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | MazG family protein; KEGG: kpu:KP1_4397 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | 0.569 |
| ADO47202.1 | pyrG | Entcl_0930 | Entcl_0934 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.498 |
| ADO47202.1 | rlmD | Entcl_0930 | Entcl_0931 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.724 |
| ADO47202.1 | rsmB | Entcl_0930 | Entcl_0426 | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.578 |
| ADO47204.1 | ADO47202.1 | Entcl_0932 | Entcl_0930 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | 0.776 |
| ADO47204.1 | ADO47205.1 | Entcl_0932 | Entcl_0933 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | MazG family protein; KEGG: kpu:KP1_4397 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | 0.972 |
| ADO47204.1 | pyrG | Entcl_0932 | Entcl_0934 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.452 |
| ADO47204.1 | rlmD | Entcl_0932 | Entcl_0931 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.724 |
| ADO47204.1 | rsmB | Entcl_0932 | Entcl_0426 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.454 |
| ADO47205.1 | ADO47202.1 | Entcl_0933 | Entcl_0930 | MazG family protein; KEGG: kpu:KP1_4397 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | 0.569 |
| ADO47205.1 | ADO47204.1 | Entcl_0933 | Entcl_0932 | MazG family protein; KEGG: kpu:KP1_4397 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.972 |
| ADO47205.1 | pyrG | Entcl_0933 | Entcl_0934 | MazG family protein; KEGG: kpu:KP1_4397 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.946 |
| ADO47205.1 | rlmD | Entcl_0933 | Entcl_0931 | MazG family protein; KEGG: kpu:KP1_4397 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.557 |
| ADO47592.1 | rlmD | Entcl_1327 | Entcl_0931 | KEGG: sbc:SbBS512_E2803 dyp-type peroxidase family protein; TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase. | RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.499 |
| pnp | pyrG | Entcl_0533 | Entcl_0934 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.739 |
| pnp | rlmD | Entcl_0533 | Entcl_0931 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.446 |
| pnp | rsmB | Entcl_0533 | Entcl_0426 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.527 |
| pyrG | ADO47202.1 | Entcl_0934 | Entcl_0930 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | KEGG: sew:SeSA_A3117 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. | 0.498 |