| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADO46765.1 | ADO46772.1 | Entcl_0487 | Entcl_0494 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.490 |
| ADO46765.1 | ADO47248.1 | Entcl_0487 | Entcl_0976 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | 0.585 |
| ADO46765.1 | ADO48828.1 | Entcl_0487 | Entcl_2578 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; KEGG: kpu:KP1_2376 hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver. | 0.987 |
| ADO46765.1 | ADO50320.1 | Entcl_0487 | Entcl_4087 | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | Manually curated; TIGRFAM: formate dehydrogenase, alpha subunit; KEGG: kpe:KPK_5187 formate dehydrogenase H, alpha subunit, selenocysteine-containing; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.434 |
| ADO46772.1 | ADO46765.1 | Entcl_0494 | Entcl_0487 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | 0.490 |
| ADO46772.1 | ADO47248.1 | Entcl_0494 | Entcl_0976 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | 0.812 |
| ADO46772.1 | ADO48828.1 | Entcl_0494 | Entcl_2578 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; KEGG: kpu:KP1_2376 hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver. | 0.490 |
| ADO47247.1 | ADO47248.1 | Entcl_0975 | Entcl_0976 | PFAM: TOBE domain-containing protein; KEGG: cko:CKO_04088 hypothetical protein. | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | 0.664 |
| ADO47247.1 | ADO47249.1 | Entcl_0975 | Entcl_0977 | PFAM: TOBE domain-containing protein; KEGG: cko:CKO_04088 hypothetical protein. | KEGG: ecm:EcSMS35_2855 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | 0.448 |
| ADO47247.1 | ADO47250.1 | Entcl_0975 | Entcl_0978 | PFAM: TOBE domain-containing protein; KEGG: cko:CKO_04088 hypothetical protein. | KEGG: cko:CKO_04085 hypothetical protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family. | 0.448 |
| ADO47247.1 | ADO47251.1 | Entcl_0975 | Entcl_0979 | PFAM: TOBE domain-containing protein; KEGG: cko:CKO_04088 hypothetical protein. | KEGG: kpu:KP1_4333 hydrogenase assembly chaperone; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC). | 0.477 |
| ADO47247.1 | ADO47252.1 | Entcl_0975 | Entcl_0980 | PFAM: TOBE domain-containing protein; KEGG: cko:CKO_04088 hypothetical protein. | Hydrogenase accessory protein HypB; KEGG: cro:ROD_30841 hydrogenase isoenzymes nickel incorporation protein; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K. | 0.453 |
| ADO47248.1 | ADO46765.1 | Entcl_0976 | Entcl_0487 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. | 0.585 |
| ADO47248.1 | ADO46772.1 | Entcl_0976 | Entcl_0494 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.812 |
| ADO47248.1 | ADO47247.1 | Entcl_0976 | Entcl_0975 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | PFAM: TOBE domain-containing protein; KEGG: cko:CKO_04088 hypothetical protein. | 0.664 |
| ADO47248.1 | ADO47249.1 | Entcl_0976 | Entcl_0977 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | KEGG: ecm:EcSMS35_2855 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | 0.818 |
| ADO47248.1 | ADO47250.1 | Entcl_0976 | Entcl_0978 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | KEGG: cko:CKO_04085 hypothetical protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family. | 0.597 |
| ADO47248.1 | ADO47251.1 | Entcl_0976 | Entcl_0979 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | KEGG: kpu:KP1_4333 hydrogenase assembly chaperone; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC). | 0.612 |
| ADO47248.1 | ADO47252.1 | Entcl_0976 | Entcl_0980 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | Hydrogenase accessory protein HypB; KEGG: cro:ROD_30841 hydrogenase isoenzymes nickel incorporation protein; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K. | 0.593 |
| ADO47248.1 | ADO47254.1 | Entcl_0976 | Entcl_0982 | Transcriptional regulator, NifA subfamily, Fis Family; KEGG: kpu:KP1_4336 formate hydrogen-lyase transcriptional activator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein. | KEGG: cro:ROD_30861 formate hydrogenlyase regulatory protein. | 0.659 |