STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO47267.1(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (739 aa)    
Predicted Functional Partners:
ADO47249.1
KEGG: ecm:EcSMS35_2855 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
 
 0.974
ADO47251.1
KEGG: kpu:KP1_4333 hydrogenase assembly chaperone; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.862
ADO48711.1
Hydrogenase assembly chaperone hypC/hupF; KEGG: yen:YE3602A hydrogenase 2 accessory protein HypG; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.858
ADO47250.1
KEGG: cko:CKO_04085 hypothetical protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family.
 
  
 0.855
ADO48710.1
KEGG: yen:YE3602 hydrogenase isoenzymes formation protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family.
 
  
 0.855
ADO48716.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: eca:ECA1228 hydrogenase 2 large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.845
ADO48715.1
Hydrogenase expression/formation protein; KEGG: eca:ECA1229 hydrogenase 2 maturation endopeptidase; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein.
 
   
 0.837
ADO47252.1
Hydrogenase accessory protein HypB; KEGG: cro:ROD_30841 hydrogenase isoenzymes nickel incorporation protein; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
   
 0.825
ADO48712.1
KEGG: yen:YE3603 hydrogenase isoenzymes nickel incorporation protein; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
   
 0.825
hypA-2
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.822
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.